Motif ID: NFY{A,B,C}.p2

Z-value: 4.037


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFYCchr1_+_411574930.948.2e-08Click!
NFYAchr6_+_410406870.871.1e-05Click!
NFYBchr12_-_1045318750.233.9e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_24105572 7.328 NM_005794
NM_182908
DHRS2

dehydrogenase/reductase (SDR family) member 2

chr17_+_80416530 5.905 NM_001083608
NM_012336
NM_031968
NARF


nuclear prelamin A recognition factor


chr17_+_80416606 5.785 NARF
nuclear prelamin A recognition factor
chr17_-_56595192 5.356 NM_004687
MTMR4
myotubularin related protein 4
chr17_-_38574042 5.192 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr17_-_47841468 4.921 FAM117A
family with sequence similarity 117, member A
chr17_+_26646120 4.903 NM_014573
TMEM97
transmembrane protein 97
chr1_+_227127937 4.737 NM_020247
ADCK3
aarF domain containing kinase 3
chr19_-_14247400 4.692 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr1_+_227127959 4.488 ADCK3
aarF domain containing kinase 3
chr4_-_174255454 4.474 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chrX_+_48114796 4.464 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr1_+_227127999 4.334 ADCK3
aarF domain containing kinase 3
chr1_+_227127993 4.331 ADCK3
aarF domain containing kinase 3
chr1_-_149399159 4.238 NM_001024599
HIST2H2BF
histone cluster 2, H2bf
chr6_+_26199712 4.120 NM_003522
HIST1H2BF
histone cluster 1, H2bf
chr9_+_131843378 4.107 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr1_+_110881944 4.021 NM_001201545
NM_022768
RBM15

RNA binding motif protein 15

chr1_+_70876863 4.000 NM_001190463
NM_001902
NM_153742
CTH


cystathionase (cystathionine gamma-lyase)


chr1_+_110882063 3.967 RBM15
RNA binding motif protein 15

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 50 entries
Enrichment   P-value GO Accession GO Term
11.80 4.78e-02 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
11.80 4.78e-02 GO:0050000 chromosome localization
11.80 4.78e-02 GO:0051303 establishment of chromosome localization
9.79 9.77e-13 GO:0031497 chromatin assembly
9.56 8.00e-12 GO:0006334 nucleosome assembly
9.44 8.59e-16 GO:0006323 DNA packaging
8.72 1.25e-11 GO:0065004 protein-DNA complex assembly
8.53 7.10e-16 GO:0071103 DNA conformation change
8.49 9.47e-11 GO:0034728 nucleosome organization
8.29 9.60e-04 GO:0000819 sister chromatid segregation
8.18 4.92e-11 GO:0071824 protein-DNA complex subunit organization
7.95 5.60e-03 GO:0000070 mitotic sister chromatid segregation
7.10 2.62e-10 GO:0006333 chromatin assembly or disassembly
6.21 3.99e-04 GO:0000236 mitotic prometaphase
5.25 1.85e-02 GO:0007088 regulation of mitosis
5.25 1.85e-02 GO:0051783 regulation of nuclear division
5.14 1.17e-11 GO:0000087 M phase of mitotic cell cycle
4.99 1.88e-10 GO:0000280 nuclear division
4.99 1.88e-10 GO:0007067 mitosis
4.96 1.86e-03 GO:0000086 G2/M transition of mitotic cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 20 of 41 entries
Enrichment   P-value GO Accession GO Term
28.32 1.50e-02 GO:0000778 condensed nuclear chromosome kinetochore
25.17 1.41e-03 GO:0031616 spindle pole centrosome
18.88 5.64e-04 GO:0000780 condensed nuclear chromosome, centromeric region
13.49 4.12e-03 GO:0042613 MHC class II protein complex
11.85 1.91e-11 GO:0000786 nucleosome
8.31 9.75e-06 GO:0000794 condensed nuclear chromosome
7.64 7.90e-09 GO:0032993 protein-DNA complex
7.42 3.39e-05 GO:0000922 spindle pole
5.81 2.38e-07 GO:0000775 chromosome, centromeric region
5.62 4.16e-07 GO:0000793 condensed chromosome
5.23 9.14e-03 GO:0000779 condensed chromosome, centromeric region
4.97 5.40e-03 GO:0000776 kinetochore
4.95 3.62e-02 GO:0000777 condensed chromosome kinetochore
4.81 3.52e-09 GO:0000785 chromatin
4.73 8.20e-18 GO:0044427 chromosomal part
4.35 3.59e-18 GO:0005694 chromosome
4.30 2.95e-05 GO:0005819 spindle
4.20 9.50e-05 GO:0044454 nuclear chromosome part
4.18 4.46e-06 GO:0000228 nuclear chromosome
3.18 7.47e-03 GO:0005813 centrosome

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
5.40 2.27e-02 GO:0003697 single-stranded DNA binding
1.76 1.99e-05 GO:0003677 DNA binding
1.66 2.18e-02 GO:0005524 ATP binding
1.63 3.19e-02 GO:0032559 adenyl ribonucleotide binding
1.62 3.61e-02 GO:0030554 adenyl nucleotide binding
1.55 1.07e-04 GO:0003676 nucleic acid binding
1.09 1.84e-02 GO:0005488 binding